Direct Meds GLP-1 vs Enhance MD: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Direct Meds GLP-1 beats Enhance MD overall, scoring 7.9/10 vs 7.8/10. Enhance MD is more affordable at $212/mo vs $297/mo. Choose Direct Meds GLP-1 for users wanting simple, all-inclusive pricing without insuranc. Choose Enhance MD for budget-conscious users interested in combination therapies.
A side-by-side comparison of Direct Meds GLP-1 and Enhance MD covering pricing, scores, medication types, insurance, and more to help you decide.
Direct Meds GLP-1
#13 of 40Straightforward compounded GLP-1 program with transparent all-inclusive pricing and no hidden fees.
Visit Direct Meds GLP-1Enhance MD
#17 of 40Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.
Visit Enhance MD| Feature | Direct Meds GLP-1 | Enhance MD |
|---|---|---|
| Our Score | 7.9/10 | 7.8/10 |
| Starting Price | $297/mo | $212/mo |
| Medication Type | Compounded | Both |
| Insurance Accepted | No | No |
| Best For | Users wanting simple, all-inclusive pricing without insurance | Budget-conscious users interested in combination therapies |
| Ranking | #13 | #17 |
Pros & Cons Compared
Direct Meds GLP-1
Pros
- +True all-inclusive pricing — $280/mo covers medication, consultations, shipping, and pharmacy fees with no add-ons
- +Clear dose-based pricing published on their site — no surprise cost increases when titrating up
- +Fast pharmacy fulfillment: most orders ship within 48 hours of provider approval
- +Responsive customer support with live chat available during business hours
Cons
- −Compounded medications only — cannot prescribe brand-name Wegovy, Zepbound, or Ozempic
- −At $280/mo for compounded-only, it's pricier than competitors like Henry Meds ($199) or TrimRx ($179)
Enhance MD
Pros
- +$115/mo starting price with access to both brand-name and compounded — rare at this price point
- +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
- +Quick asynchronous consultations — most patients approved within 24 hours without video calls
- +Flexible dosing: can start at lower doses than standard protocols for sensitive patients
Cons
- −Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
- −No insurance billing and limited customer support hours (business days only, no weekends)
Our Verdict
Direct Meds GLP-1 edges out Enhance MD with a score of 7.9/10 vs 7.8/10. If budget is your priority, Enhance MD starts at $212/mo compared to Direct Meds GLP-1's $297/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Direct Meds GLP-1 if you want: users wanting simple, all-inclusive pricing without insurance. Choose Enhance MD if you want: budget-conscious users interested in combination therapies.