Direct Meds GLP-1 vs Sesame Care: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Direct Meds GLP-1 and Sesame Care are tied at 7.9/10. Sesame Care is more affordable at $99/mo vs $297/mo. Choose Direct Meds GLP-1 for users wanting simple, all-inclusive pricing without insuranc. Choose Sesame Care for users who want cheap doctor visits and already have insuranc.

A side-by-side comparison of Direct Meds GLP-1 and Sesame Care covering pricing, scores, medication types, insurance, and more to help you decide.

Direct Meds GLP-1

#13 of 40
7.9/10

Straightforward compounded GLP-1 program with transparent all-inclusive pricing and no hidden fees.

Visit Direct Meds GLP-1

Sesame Care

#10 of 40
7.9/10

Ultra-affordable telehealth platform offering low-cost doctor consultations for GLP-1 prescriptions, ideal for insured patients.

Visit Sesame Care
FeatureDirect Meds GLP-1Sesame Care
Our Score7.9/107.9/10
Starting Price$297/mo$99/mo
Medication TypeCompoundedBoth
Insurance AcceptedNoYes
Best ForUsers wanting simple, all-inclusive pricing without insuranceUsers who want cheap doctor visits and already have insurance to cover brand-name medications
Ranking#13#10

Pros & Cons Compared

Direct Meds GLP-1

Pros

  • +True all-inclusive pricing — $280/mo covers medication, consultations, shipping, and pharmacy fees with no add-ons
  • +Clear dose-based pricing published on their site — no surprise cost increases when titrating up
  • +Fast pharmacy fulfillment: most orders ship within 48 hours of provider approval
  • +Responsive customer support with live chat available during business hours

Cons

  • Compounded medications only — cannot prescribe brand-name Wegovy, Zepbound, or Ozempic
  • At $280/mo for compounded-only, it's pricier than competitors like Henry Meds ($199) or TrimRx ($179)

Sesame Care

Pros

  • +Extremely low consultation cost
  • +Insurance accepted
  • +Both medication types
  • +Simple booking

Cons

  • Consultation only (meds separate)
  • Less hand-holding

Our Verdict

Direct Meds GLP-1 and Sesame Care are closely matched with identical scores of 7.9/10. If budget is your priority, Sesame Care starts at $99/mo compared to Direct Meds GLP-1's $297/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Sesame Care offers both brand-name and compounded medications, giving you more flexibility. Choose Direct Meds GLP-1 if you want: users wanting simple, all-inclusive pricing without insurance. Choose Sesame Care if you want: users who want cheap doctor visits and already have insurance to cover brand-name medications.

Try Direct Meds GLP-1

Starting at $297/mo

Visit Direct Meds GLP-1

Try Sesame Care

Starting at $99/mo

Visit Sesame Care