Enhance MD vs MyStart Health: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Enhance MD beats MyStart Health overall, scoring 7.8/10 vs 7.7/10. Enhance MD is more affordable at $212/mo vs $249/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose MyStart Health for users who value a money-back weight-loss guarantee and price.

A side-by-side comparison of Enhance MD and MyStart Health covering pricing, scores, medication types, insurance, and more to help you decide.

Higher Rated

Enhance MD

#17 of 40
7.8/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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MyStart Health

#20 of 40
7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

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FeatureEnhance MDMyStart Health
Our Score7.8/107.7/10
Starting Price$212/mo$249/mo
Medication TypeBothBoth
Insurance AcceptedNoNo
Best ForBudget-conscious users interested in combination therapiesUsers who value a money-back weight-loss guarantee and price-lock protection
Ranking#17#20

Pros & Cons Compared

Enhance MD

Pros

  • +$115/mo starting price with access to both brand-name and compounded — rare at this price point
  • +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
  • +Quick asynchronous consultations — most patients approved within 24 hours without video calls
  • +Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

  • Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
  • No insurance billing and limited customer support hours (business days only, no weekends)

MyStart Health

Pros

  • +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates — a genuine differentiator
  • +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
  • +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
  • +HSA/FSA eligible — can use pre-tax health savings to pay for treatment

Cons

  • Cash-pay only — no insurance accepted, which limits options for patients with GLP-1 coverage
  • Only available in select states — not all 50, and the exact state list isn't published
  • Compounded medications only — no brand-name GLP-1 options available

Our Verdict

Enhance MD edges out MyStart Health with a score of 7.8/10 vs 7.7/10. If budget is your priority, Enhance MD starts at $212/mo compared to MyStart Health's $249/mo. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose MyStart Health if you want: users who value a money-back weight-loss guarantee and price-lock protection.

Try Enhance MD

Starting at $212/mo

Visit Enhance MD

Try MyStart Health

Starting at $249/mo

Visit MyStart Health