Enhance MD vs TMates: Which GLP-1 Provider Is Better?
By Iacob Pastina, Independent Researcher
Enhance MD and TMates are tied at 7.8/10. TMates is more affordable at $199/mo vs $212/mo. Choose Enhance MD for budget-conscious users interested in combination therapies. Choose TMates for users with insurance who want a coached glp-1 program with m.
A side-by-side comparison of Enhance MD and TMates covering pricing, scores, medication types, insurance, and more to help you decide.
Enhance MD
#17 of 40Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.
Visit Enhance MDTMates
#15 of 40Insurance-friendly compounded GLP-1 program with coaching support and multiple medication options.
Visit TMates| Feature | Enhance MD | TMates |
|---|---|---|
| Our Score | 7.8/10 | 7.8/10 |
| Starting Price | $212/mo | $199/mo |
| Medication Type | Both | Compounded |
| Insurance Accepted | No | Yes |
| Best For | Budget-conscious users interested in combination therapies | Users with insurance who want a coached GLP-1 program with multiple medication options |
| Ranking | #17 | #15 |
Pros & Cons Compared
Enhance MD
Pros
- +$115/mo starting price with access to both brand-name and compounded — rare at this price point
- +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
- +Quick asynchronous consultations — most patients approved within 24 hours without video calls
- +Flexible dosing: can start at lower doses than standard protocols for sensitive patients
Cons
- −Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
- −No insurance billing and limited customer support hours (business days only, no weekends)
TMates
Pros
- +Accepts major insurance (Aetna, Cigna, UnitedHealthcare, BCBS) — one of the few compounded GLP-1 providers to do so
- +100% no-questions-asked refund policy — contact support for a full refund if unsatisfied
- +24/7 support with health coaching, nutrition guidance, and progress tracking included
- +Available in all 50 states plus Puerto Rico and territories
Cons
- −90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
- −Insurance coverage for compounded medications varies significantly — verify coverage before enrolling
- −Heavy press-release marketing and limited independent reviews make it hard to verify claims
Our Verdict
Enhance MD and TMates are closely matched with identical scores of 7.8/10. If budget is your priority, TMates starts at $199/mo compared to Enhance MD's $212/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Enhance MD if you want: budget-conscious users interested in combination therapies. Choose TMates if you want: users with insurance who want a coached glp-1 program with multiple medication options.