MyStart Health vs TMates: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

TMates beats MyStart Health overall, scoring 7.8/10 vs 7.7/10. TMates is more affordable at $199/mo vs $249/mo. Choose MyStart Health for users who value a money-back weight-loss guarantee and price. Choose TMates for users with insurance who want a coached glp-1 program with m.

A side-by-side comparison of MyStart Health and TMates covering pricing, scores, medication types, insurance, and more to help you decide.

MyStart Health

#20 of 40
7.7/10

GLP-1 provider offering a unique money-back guarantee and price-lock protection for long-term cost certainty.

Visit MyStart Health
Higher Rated

TMates

#15 of 40
7.8/10

Insurance-friendly compounded GLP-1 program with coaching support and multiple medication options.

Visit TMates
FeatureMyStart HealthTMates
Our Score7.7/107.8/10
Starting Price$249/mo$199/mo
Medication TypeBothCompounded
Insurance AcceptedNoYes
Best ForUsers who value a money-back weight-loss guarantee and price-lock protectionUsers with insurance who want a coached GLP-1 program with multiple medication options
Ranking#20#15

Pros & Cons Compared

MyStart Health

Pros

  • +Price Lock Guarantee ensures your monthly rate never increases even as your GLP-1 dose escalates — a genuine differentiator
  • +Access to 600+ board-certified doctors with unlimited clinician messaging at no additional cost
  • +Competitive pricing at $149-$179/mo for compounded semaglutide with free shipping included
  • +HSA/FSA eligible — can use pre-tax health savings to pay for treatment

Cons

  • Cash-pay only — no insurance accepted, which limits options for patients with GLP-1 coverage
  • Only available in select states — not all 50, and the exact state list isn't published
  • Compounded medications only — no brand-name GLP-1 options available

TMates

Pros

  • +Accepts major insurance (Aetna, Cigna, UnitedHealthcare, BCBS) — one of the few compounded GLP-1 providers to do so
  • +100% no-questions-asked refund policy — contact support for a full refund if unsatisfied
  • +24/7 support with health coaching, nutrition guidance, and progress tracking included
  • +Available in all 50 states plus Puerto Rico and territories

Cons

  • 90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
  • Insurance coverage for compounded medications varies significantly — verify coverage before enrolling
  • Heavy press-release marketing and limited independent reviews make it hard to verify claims

Our Verdict

TMates edges out MyStart Health with a score of 7.8/10 vs 7.7/10. If budget is your priority, TMates starts at $199/mo compared to MyStart Health's $249/mo. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. MyStart Health offers both brand-name and compounded medications, giving you more flexibility. Choose MyStart Health if you want: users who value a money-back weight-loss guarantee and price-lock protection. Choose TMates if you want: users with insurance who want a coached glp-1 program with multiple medication options.

Try MyStart Health

Starting at $249/mo

Visit MyStart Health

Try TMates

Starting at $199/mo

Visit TMates