Sesame Care vs SynergyRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

Sesame Care beats SynergyRx overall, scoring 7.9/10 vs 7.6/10. Sesame Care is more affordable at $99/mo vs $199/mo. Choose Sesame Care for users who want cheap doctor visits and already have insuranc. Choose SynergyRx for users who want predictable bundled pricing with 24/7 support.

A side-by-side comparison of Sesame Care and SynergyRx covering pricing, scores, medication types, insurance, and more to help you decide.

Higher Rated

Sesame Care

#10 of 40
7.9/10

Ultra-affordable telehealth platform offering low-cost doctor consultations for GLP-1 prescriptions, ideal for insured patients.

Visit Sesame Care

SynergyRx

#22 of 40
7.6/10

Bundled GLP-1 program with predictable pricing and round-the-clock support access for peace of mind.

Visit SynergyRx
FeatureSesame CareSynergyRx
Our Score7.9/107.6/10
Starting Price$99/mo$199/mo
Medication TypeBothBoth
Insurance AcceptedYesNo
Best ForUsers who want cheap doctor visits and already have insurance to cover brand-name medicationsUsers who want predictable bundled pricing with 24/7 support access
Ranking#10#22

Pros & Cons Compared

Sesame Care

Pros

  • +Extremely low consultation cost
  • +Insurance accepted
  • +Both medication types
  • +Simple booking

Cons

  • Consultation only (meds separate)
  • Less hand-holding

SynergyRx

Pros

  • +Oral dissolving tablets for BOTH semaglutide AND tirzepatide — one of the few platforms with needle-free tirzepatide
  • +Free expedited shipping included with all orders
  • +24/7 support with unlimited messaging — no per-visit fees for follow-up questions or dose adjustments
  • +Both compounded and brand-name options available (Ozempic, Wegovy, Mounjaro)

Cons

  • Casper, WY registration address and limited independent reviews raise legitimacy questions
  • Brand-name pricing ($499-947/mo) is very high compared to direct manufacturer programs like LillyDirect
  • Company history, founding date, and ownership structure are not publicly disclosed

Our Verdict

Sesame Care edges out SynergyRx with a score of 7.9/10 vs 7.6/10. If budget is your priority, Sesame Care starts at $99/mo compared to SynergyRx's $199/mo. Sesame Care accepts insurance, which can significantly reduce your out-of-pocket costs. Choose Sesame Care if you want: users who want cheap doctor visits and already have insurance to cover brand-name medications. Choose SynergyRx if you want: users who want predictable bundled pricing with 24/7 support access.

Try Sesame Care

Starting at $99/mo

Visit Sesame Care

Try SynergyRx

Starting at $199/mo

Visit SynergyRx