TMates vs TrimRx: Which GLP-1 Provider Is Better?

By Iacob Pastina, Independent Researcher

TrimRx beats TMates overall, scoring 8.3/10 vs 7.8/10. Choose TMates for users with insurance who want a coached glp-1 program with m. Choose TrimRx for users who want affordable compounded glp-1s with transparent.

A side-by-side comparison of TMates and TrimRx covering pricing, scores, medication types, insurance, and more to help you decide.

TMates

#15 of 40
7.8/10

Insurance-friendly compounded GLP-1 program with coaching support and multiple medication options.

Visit TMates
Higher Rated

TrimRx

#7 of 40
8.3/10

Budget-friendly compounded GLP-1 provider with straightforward pricing and a focus on accessibility.

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FeatureTMatesTrimRx
Our Score7.8/108.3/10
Starting Price$199/mo$199/mo
Medication TypeCompoundedCompounded
Insurance AcceptedYesNo
Best ForUsers with insurance who want a coached GLP-1 program with multiple medication optionsUsers who want affordable compounded GLP-1s with transparent, all-inclusive pricing
Ranking#15#7

Pros & Cons Compared

TMates

Pros

  • +Accepts major insurance (Aetna, Cigna, UnitedHealthcare, BCBS) — one of the few compounded GLP-1 providers to do so
  • +100% no-questions-asked refund policy — contact support for a full refund if unsatisfied
  • +24/7 support with health coaching, nutrition guidance, and progress tracking included
  • +Available in all 50 states plus Puerto Rico and territories

Cons

  • 90-second assessment quiz suggests convenience over clinical thoroughness compared to competitors with full medical intakes
  • Insurance coverage for compounded medications varies significantly — verify coverage before enrolling
  • Heavy press-release marketing and limited independent reviews make it hard to verify claims

TrimRx

Pros

  • +$179/mo all-inclusive for compounded semaglutide — one of the lowest prices for a full-service program
  • +Onboarding takes under 15 minutes with same-day provider review for most applications
  • +Published patient reviews averaging 4.5+ stars across third-party platforms
  • +Free medication replacement if your shipment is lost or damaged in transit

Cons

  • Compounded semaglutide only — no brand-name options and no tirzepatide (compounded or otherwise)
  • No insurance billing, and no superbill provided for out-of-network reimbursement

Our Verdict

TrimRx edges out TMates with a score of 8.3/10 vs 7.8/10. TMates accepts insurance, which can significantly reduce your out-of-pocket costs. Choose TMates if you want: users with insurance who want a coached glp-1 program with multiple medication options. Choose TrimRx if you want: users who want affordable compounded glp-1s with transparent, all-inclusive pricing.

Try TMates

Starting at $199/mo

Visit TMates

Try TrimRx

Starting at $199/mo

Visit TrimRx